CDC Cancer Team Fired; NIH Ordered to Study Transgender 'Regret'; AI May Help in OUD (MedPage Today) -- Note that some links may require registration or subscription. MedPage Today is collecting stories of HHS staffers across all agencies affected by Trump administration cuts. If you want to share your story, please email MPT_Editorial...
'Natural Experiment' Ties Shingles Vaccine to Reduced Dementia Risk (MedPage Today) -- Vaccination against herpes zoster, or shingles, was tied to significantly less dementia risk, a large-scale analysis of electronic health records in Wales showed.
Receiving the live-attenuated zoster vaccine (Zostavax) reduced...
AI Chatbot Helps Mental Health; Neuroplastogen for PTSD: Magic Mushroom Dispensaries (MedPage Today) -- A fully generative artificial intelligence (AI) therapy chatbot was effective for reducing mental health symptoms, including depression, anxiety, and eating disorders in an 8-week randomized trial. (NEJM AI)
Axsome Therapeutics...
Novel Blood Test Tracks Alzheimer's Progression (MedPage Today) -- A novel plasma-based assay was more strongly associated with tau tangle pathology in Alzheimer's disease than other established blood biomarkers, researchers said.
The assay measured a new plasma tau species known as endogenously...
Are Hormonal Contraceptives Tied to Postpartum Depression? (MedPage Today) -- Among first-time mothers in Denmark, initiating hormonal contraception postpartum was associated with an "instantaneous" higher risk of depression, a population-based cohort study found.
Compared to no use, hormonal contraceptive...
New Trump Attack on HHS Staff; Luigi Mangione Ballot Measure; Ativan's Star TV Role (MedPage Today) -- Note that some links may require registration or subscription.
MedPage Today is collecting stories of HHS staffers across all agencies affected by Trump administration cuts. If you want to share your story, please email MPT...
'I Am Going Through Hell': Job Loss, Mental Health, and the Fate of Federal Workers (MedPage Today) -- The NIH employee said she knew things would be difficult for federal workers after Donald Trump was elected. But she never imagined it would be like this.
Focused on Alzheimer's and other dementia research, the worker is among...
Every Hospital Should Offer Addiction Treatment (MedPage Today) -- Two people are wheeled into a hospital at the same time: one for a heart attack and one for an opioid overdose. You might expect that both individuals will be offered standard of care treatment for their respective conditions...
Highly Educated People Face Steeper Cognitive Decline After Stroke (MedPage Today) -- Education level was associated with the trajectory of cognitive decline following stroke, an individual participant data meta-analysis of four U.S. cohort studies showed.
After adjusting for pre-stroke cognition, college-educated...
Trump Turns Homelessness Response Away From Housing, Toward Forced Treatment (MedPage Today) -- President Donald Trump is vowing a new approach to getting homeless people off the streets by forcibly moving those living outside into large camps while mandating mental health and addiction treatment -- an aggressive departure...
Alzheimer's Research Caught in Trump Funding Delays (MedPage Today) -- Research and patient care may quickly stop at 14 of the country's Alzheimer's Disease Research Centers (ADRCs) due to lack of funds.
Funding has effectively been halted at 14 of the nation's 35 ADRCs after the Trump administration...
Quetiapine May Be Better Option Than Lithium for Treatment-Resistant Depression (MedPage Today) -- Quetiapine (Seroquel) was more clinically effective than lithium as a first-line augmentation option in treatment-resistant depression and likely was more cost-effective, a pragmatic multicenter clinical trial suggested.
Over...
Americans Unhappier Than Ever; Smartphone Brain Rot? TikToks Miss Mark on ADHD (MedPage Today) -- The U.S. ranked 24th on this year's World Happiness Report, falling to its lowest-ever spot. (CBS News)
College students who were night owls had higher odds of depressive symptoms compared with early birds, a cross-sectional...
Surprising Findings From New Research About Dementia and Marriage (MedPage Today) -- Unmarried people had a lower risk of dementia than those who were married, data from an 18-year cohort study of 24,000 older adults suggested.
In models adjusted for age and sex, never-married (HR 0.60, 95% CI 0.52-0.71), divorced...
Trump Administration Cancels at Least 68 Grants Focused on LGBTQ Health Questions (MedPage Today) -- A surge of grant cancellations hit researchers focused on the health of gay, lesbian, and transgender people last week, as the Trump administration continues to target what it describes as ideologically driven science.
Last...
Alzheimer's May Be Delayed in Asymptomatic Patients, Small Trial Suggests (MedPage Today) -- Long-term removal of amyloid beta in people genetically destined to develop Alzheimer's disease may have delayed symptoms and disease progression, data from the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) suggested...
Dementia Risk Rises for Older Women With Changing Sleep Patterns (MedPage Today) -- Changes in sleep patterns among cognitively unimpaired women in their 80s were associated with an increased risk of dementia, a longitudinal study showed.
Compared with women who had stable sleep patterns, those who had increasing...
Microdosing LSD Fails to Ease ADHD Symptoms in Small Trial (MedPage Today) -- Low-dose treatment with lysergic acid diethylamide (LSD) failed to improve symptoms of attention deficit-hyperactivity disorder (ADHD) in adults, a double-blind randomized phase IIa trial showed.
After 6 weeks, the group who...
New Data on GLP-1s and Suicide; Sleep and Conspiracy Theories; Xanax's Dark Side (MedPage Today) -- A meta-analysis of 27 randomized clinical trials found very low incidence of suicide-related adverse events among patients with diabetes or obesity on GLP-1 receptor agonists. (JAMA Psychiatry)
Installing safety nets on the...
Without Federal Action, States Wrestle With Kratom Regulation (MedPage Today) -- HELENA, Mont. -- Montana lawmakers are grappling with how -- if at all -- the state should rein in kratom, an unregulated plant-derived substance with addictive properties sold mainly as a mood and energy booster at gas...
Could Updating Urine Drug Screenings in Pregnancy Reduce Racial Inequities? (MedPage Today) -- For peripartum urine drug screening, removing some indications and implementing a clinician-facing clinical decision support tool reduced disparities between Black and white patients, a quality improvement study found.
After...