- AI may help researchers with medical chart review, study finds
Researchers trained a large language model to read medical charts, looking for signs that kids with ADHD received the right follow-up care when using new medications.
- Poor vascular health accelerates brain aging
Using an AI tool, researchers have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.
- AI may help researchers with medical chart review
Researchers trained a large language model to read medical charts, looking for signs that kids with ADHD received the right follow-up care when using new medications.
- Integrating GABA and dopamine signals to regulate meal initiation
When you are feeling hungry, the brain takes the necessary steps toward consuming a meal. Many of these steps are not well known, but a new study reveals brain circuits and chemical messengers that contribute to the regulation of meal initiation and food intake. The findings have implications for the development of improved therapies to manage obesity, a worldwide epidemic.
- Getting rehab earlier improves concussion outcomes
People who suffer from continued symptoms of concussion should seek a referral to physical therapy as soon as possible, new research suggests.
- Patience isn't a virtue; it's a coping mechanism
Impatience, studies of more than 1,200 people found, is the emotion people feel when they face a delay that seems unfair, unreasonable, or inappropriate -- like a traffic jam outside of rush hour, or a meeting that should have ended 15 minutes ago. Patience is the form of emotion regulation we use to cope with those feelings of impatience.
- Machine psychology: A bridge to general AI?
Artificial intelligence that is as intelligent as humans may become possible thanks to psychological learning models, combined with certain types of AI.
- Brain inflammation alters behavior according to sex, mouse study finds
Inflammation in the hippocampus -- the brain's memory center -- significantly alters motivation and behavior in mice, according to new research.
- Charting a path toward overcoming glioblastoma resistance to chemotherapy
Mutational signatures etched into the cells' genome by an anti-cancer drug called temozolomide (TMZ) uncover an Achilles' heel for TMZ chemotherapy resistance, according to new research.
- Antibody that neutralizes inhibitory factors involved in nerve regeneration leads to enhanced motor function after acute spinal cord injury
Antibodies can improve the rehabilitation of people with acute spinal cord injury. Researchers have investigated this with promising results. For the first time, it was possible to identify patient groups that displayed a clinically relevant treatment effect.
- Study finds slowing of age-related declines in older adults
A new study reveals significant improvements in the health of older adults when compared to previous generations.
- Effect of somatosensory electrical stimulation on hand choice
Hand choice, an unconscious decision, is influenced by target-related information, but if these are non-informative, the choice will be approximately 50-50. In this equilibrium situation, non-target information may also aid in decision-making, but no research has demonstrated this. Now, researchers have investigated the effect of somatosensory stimulation on motor decisions in healthy participants. The results revealed that wrist stimulation significantly increased the likelihood of choosing the stimulated hand, highlighting its application in stroke rehabilitation.
- The surprising role of gut infection in Alzheimer's disease
Researchers have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people. It is believed most humans are exposed to this virus -- called cytomegalovirus or HCMV -- during the first few decades of life. According to the new research, in some people, the virus may linger in an active state in the gut, where it may travel to the brain via the vagus nerve -- a critical information highway that connects the gut and brain. Once there, the virus can change the immune system and contribute to other changes associated with Alzheimer's disease. This virus may be a target for antiviral treatments.
- How to deal with narcissists at home and at work
The best way to deal with narcissistic people in your personal life may be the hardest advice to take, according to an expert who has studied narcissism for more than 20 years. The best course of action is to identify narcissistic people early on and get them out of your life, said the professor of psychology.
- Developmental disorder discovery could lead to better treatments for Rett syndrome
New discoveries about the severe developmental disorder known as Rett syndrome could open the door to better treatments for the devastating, life-shortening condition.
- Genetic discovery links new gene to autism spectrum disorder
New research has identified previously unknown genetic links to autism spectrum disorder (ASD), providing new insights into the genetic underpinnings of the condition.
- First successful clinical trial of VU319 brings Alzheimer's treatment one step closer
Phase I clinical trial of a drug was successfully completed, with promise to treat Alzheimer's and other neurodegenerative diseases. The compound, named VU319, is the first end-to-end drug discovery effort related to memory loss, starting from the earliest basic science research through human clinical trials.
- Combining long- and short-read sequencing in single cells reveals new mRNAs in neurodegenerative diseases
Researchers have combined two sequencing technologies in single cells to find new differences in mRNAs resulting from Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease.
- Drinking coffee may help prevent mental decline in people with atrial fibrillation
A study of more than 2,400 people with atrial fibrillation, who had an average age of 73, found that drinking more than five cups of caffeinated coffee daily was associated with better performance on an array of cognitive tests than drinking less than one cup or avoiding coffee altogether.
- New study reveals how brain stimulation improves cognition, decision-making in mental health disorders
Researchers have uncovered important insights that could improve how mental health conditions are treated with brain stimulation therapy -- a treatment where electrical signals are used to stimulate specific parts of the brain.
- Research shows how music can reduce distress
A new study has demonstrated for the first time how and why music can reduce distress and agitation for people with advanced dementia. The study involved interviews with staff and music therapists on inpatient mental health dementia wards, a review of published research, and a national survey of UK healthcare professionals.
- Role 'workhorse protein' plays in keeping the nervous system running smoothly
A team of researchers shows how proteins called 'chaperones' are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission breaks down, devastating diseases such as Alzheimer's and Parkinson's along with many others, can occur. The team's research provides new understanding of how the most crucial part of the process works and is a stepping stone toward understanding the underlying mechanics of neurodegenerative diseases.
- Human-like artificial intelligence may face greater blame for moral violations
In a new study, participants tended to assign greater blame to artificial intelligences (AIs) involved in real-world moral transgressions when they perceived the AIs as having more human-like minds.
- Researchers reveal mechanisms underlying Sjögren's disease
Researchers are closer to understanding what drives the autoimmune disorder Sj gren's disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interferon. Their latest study finds that impaired regulatory T cells are a critical contributing factor to Sj gren's disease in both mice and humans, and identifies an existing rheumatology drug as a promising therapy for the disease.
- Dyslexia genetics linked to brain structure
Dyslexia is a common learning difficulty in which genes often play a role. How do genes associated with dyslexia relate to brain structure in the general population? In a large-scale study, a team of scientists found that genetic variants that increase the chance of dyslexia were associated with differences in brain areas involved in motor coordination, vision, and language.