- Aldehyde-Based Surface Disinfectants May Reduce Hepatitis A Virus Transmission, Study Finds
Among the 9 surface disinfectants studied, only 2 demonstrated a reduction in viral titer below the limit of detection.
- Caveolin-1 May Be A Promising Therapeutic Target For Multiple Myeloma, Study Finds
CAV-1 is a key protein in lipid rafts that helps control cellular processes such as growth, survival, and migration.
- FDA Approves Inebilizumab to Treat Adult Patients With IgG4-RD
This action makes inebilizumab the first and only FDA-approved treatment for adults with immunoglobulin G4-related disease (IgG4-RD).
- Low HDL-C, Triglyceride Levels in Late Life Independently Associated With Alzheimer Disease and Related Dementias
Notably, high levels of high-density lipoprotein cholesterol (HDL-C) were not associated with the risk of dementia following adjustments for triglyceride levels.
- Study: Prevalence of Micronutrient Deficiencies in Patients With Type 2 Diabetes
Pharmacists can address micronutrient deficiencies, aiding those with type 2 diabetes as they face a higher risk.
- Siremadlin Demonstrates Efficacy, Safety in Treatment of Patients With TP53 Wild-Type Chronic Lymphocytic Leukemia
Siremadlin is a novel, investigational, second-generation antagonist that binds to MDM2.
- Organon Expands Portfolio With Biosimilar Tocilizumab-bavi for Arthritis and COVID-19
Tocilizumab-bavi received FDA approval in September 2023 as the first biosimilar to tocilizumab for the treatment of various adult and pediatric arthritis conditions.
- FDA Issues Complete Response Letter to Manufacturer of Reproxalap, Treatment for Dry Eye Disease, Allergic Conjunctivitis
No manufacturing or safety issues were identified, but the FDA stated the new drug application did not demonstrate efficacy in adequate and well-controlled studies.
- The Landscape of Drug Development and the Pharmaceutical Industry in Italy: Challenges, Trends, and the Role of Generics
Generics play a crucial role in mitigating drug shortages by offering a real alternative for 80% of drugs that are becoming increasingly unavailable in Italy.
- Integrated Multi-Omic Data: Powering Precision Medicine
Through increased utilization of multi-omic data, health care professionals can revolutionize the treatment paradigm of countless diseases.
- Researchers Use CRISPR Screens to Identify Factors Influencing Trastuzumab Emtansine Sensitivity, Resistance
The predictive tool may reveal the mechanisms underlying treatment resistance in patients with HER+ breast cancer.
- FDA Grants Accelerated Approval to Atrasentan for Proteinuria Reduction in Primary IgA Nephropathy
Positive results from an interim analysis of the phase 3 ALIGN study bolstered atrasentan towards receiving accelerated approval for patients with immunoglobulin A nephropathy, a rare condition that can cause kidney failure.
- Nivolumab May Restore T-Cell Fitness Following CAR T-Cell Therapy in Patients With Multiple Myeloma
Real-time profiling of T-cell activation states in non-CAR T-cells may help guide treatment decisions.
- Interdisciplinary Approaches to Breast Cancer Care and ADC Treatment Barriers Due to Social Determinants of Health
Panelists discuss how optimizing antibody-drug conjugate (ADC) therapy in patients with metastatic breast cancer (mBC) requires interdisciplinary care, including oncologists, pharmacists, and nurses. Adherence barriers such as cost, access, and insurance are addressed via financial and social support.
- Discussing ADC Risks, Benefits, and Regimens With Patients
Panelists discuss how health care professionals use clear, tailored communication to explain antibody-drug conjugate (ADC) risks, benefits, and regimens. They provide education, address concerns, and ensure adherence through counseling and shared decision-making.
- The GLP-1 Conundrum: Insights from the 2025 Pharmacy in Focus Report
Pharmacists play a crucial role in educating patients on proper administration and adherence to GLP-1 treatments.
- ELCC 2025: Amivantamab Plus Lazertinib Effective in EGFR-Mutated NSCLC Versus Standard of Care
Nicolas Girard, MD, explains the benefits observed in the MARIPOSA clinical trial among patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) treated with amivantamab plus lazertinib.
- Single Dose of PCV20 for Toddlers Following Previous PCV13 Doses Protects Against Additional Pneumococcal Serotypes
These new phase 3 results indicate the effectiveness of the 2-dose 13-valent pneumococcal conjugate vaccine (PCV13) and 1-dose PCV20 regimens.
- Understand the 2025-2026 Flu Vaccine Composition Recommendations
The only major change is in the included strain of influenza A/H2N2 virus, which has been updated for both the egg-based and the cell- and recombinant-based vaccines.
- Revolutionizing Treatment with Bispecific Therapies: Navigating the Challenges Ahead
By decade’s end, approval of additional bispecifics is expected for hematological malignancies, solid tumors, and non-oncology conditions such as inflammatory, autoimmune, neurodegenerative and vascular diseases, and ocular disorders and infections.
- The Use of CMR in Patients With Recurrent Pericarditis Initiating Rilonacept
The registry data showed that cardiac magnetic resonance (CMR) was obtained in more clinically complex patients with recurrent pericarditis.
- FDA Approves Auto-Pure 2400 for Faster, More Accurate Tuberculosis Diagnosis
The Auto-Pure 2400 system combines liquid handling and magnetic cell isolation for efficient latent tuberculosis testing.
- Pharmacist-Driven Management of Venetoclax Ramp-Up Safe, Feasible in Patients With Chronic Lymphocytic Leukemia
Pharmacists performed weekly toxicity and tumor lysis syndrome monitoring.
- The Future of the Protecting Pharmacies in Medicaid Act Requires Advocacy
Similar legislation could also address PBM practices in commercial insurance.
- How Pharmacies Can Better Support Employees Living With Serious Mental Illness
Reducing stigma, improving mental health benefits, and addressing workload concerns all need to happen simultaneously.
- NCCN 2025: Advancing Breast Cancer Risk Assessment and Prevention Strategies
Evolving breast cancer risk models and prevention methods are necessary to improve patient outcomes, according to Sagar Sardesai, MD.
- Study: Vitamin B12 Levels Within "Normal" Range Linked to Cognitive Decline in Older Adults
Current recommended levels of vitamin B12 might not be sufficient to protect against neurological decline.
- Finerenone Shows Promise in Heart Failure and Kidney Disease Management
John Ostrominski, MD shares insights into the safety and efficacy of finerenone, based on data from the FINEARTS-HF trial.