Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.

Scientists have uncovered new details about the mechanism behind cancer progression. Researchers explored the influence the mechanical stiffening of the tumor cell's environment may have on the structure and function of the nucleus.

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts about 1 million people and kills about 30,000 people around the world every year.

Combining bioinformatics and experimetal approaches, researchers have discovered replication hubs for human norovirus, the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year. The findings could lead to designing antiviral drugs to prevent, control or treat these serious infections.

Researchers conducted a comprehensive review of Chagas disease in Switzerland. Although typically found in Latin America, Chagas disease affects between 2,000 and 4,000 people in Switzerland. The review underscores the need for improved screening and healthcare strategies to eliminate Chagas disease in Switzerland.

Researchers trained a large language model to read medical charts, looking for signs that kids with ADHD received the right follow-up care when using new medications.

Using an AI tool, researchers have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.

Researchers have been able to identify at least three distinct subtypes of a rare type of bone cancer for the first time, which could transform clinical trials and patient care.

Researchers trained a large language model to read medical charts, looking for signs that kids with ADHD received the right follow-up care when using new medications.

When you are feeling hungry, the brain takes the necessary steps toward consuming a meal. Many of these steps are not well known, but a new study reveals brain circuits and chemical messengers that contribute to the regulation of meal initiation and food intake. The findings have implications for the development of improved therapies to manage obesity, a worldwide epidemic.

New findings point to an opportunity to improve therapies that use small RNAs to silence disease-causing genes, potentially including those involved in cancer.

People who suffer from continued symptoms of concussion should seek a referral to physical therapy as soon as possible, new research suggests.

A study may explain why some patients with Crohn's disease continue to experience symptoms, even in the absence of inflammation.

A research team examined the atomic composition of enamel samples from two human teeth.

Impatience, studies of more than 1,200 people found, is the emotion people feel when they face a delay that seems unfair, unreasonable, or inappropriate -- like a traffic jam outside of rush hour, or a meeting that should have ended 15 minutes ago. Patience is the form of emotion regulation we use to cope with those feelings of impatience.

A team of chemists has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study combines biocatalytic carbon-hydrogen oxidation and radical cross-coupling, offering a streamlined and cost-effective approach to create complex, three-dimensional molecules. This innovation could help accelerate drug discovery and enhance the efficiency of medicinal chemistry.

Artificial intelligence that is as intelligent as humans may become possible thanks to psychological learning models, combined with certain types of AI.

Inflammation in the hippocampus -- the brain's memory center -- significantly alters motivation and behavior in mice, according to new research.

Mutational signatures etched into the cells' genome by an anti-cancer drug called temozolomide (TMZ) uncover an Achilles' heel for TMZ chemotherapy resistance, according to new research.

A research team found out how AHCC, a standardized extract of cultured Lentinula edodes mycelia, might be able to suppress the progression of liver fibrosis.

Antibodies can improve the rehabilitation of people with acute spinal cord injury. Researchers have investigated this with promising results. For the first time, it was possible to identify patient groups that displayed a clinically relevant treatment effect.

Researchers have discovered that certain components of so-called 'good' cholesterol -- high-density lipoproteins (HDL) -- may be associated with an increased prevalence of cardiovascular disease.

Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including cancer and neurodegenerative disorders. A protein called USP53 has been recently linked with progressive familial intrahepatic cholestasis, a hereditary liver disease in children, yet its mechanism of action has remained elusive. While its sequence made it part of a deubiquitinase family, previous attempt to detect catalytic activity had remained inconclusive. Now, a team has decoded the mode of action of USP53 and its related enzyme called USP54.

When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. Researchers have found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production.

A new study reveals significant improvements in the health of older adults when compared to previous generations.